BDBM194220 US9200001, 136

SMILES: Cc1nc(C)n(n1)-c1cc(nc(OC2CCC2)n1)[C@@H]1C[C@H]1c1nc2ccccc2n1C

InChI Key: InChIKey=CGHJKDRDXVGUTJ-IAGOWNOFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM194220 (US9200001, 136) Show SMILES Cc1nc(C)n(n1)-c1cc(nc(OC2CCC2)n1)[C@@H]1C[C@H]1c1nc2ccccc2n1C |r| Show InChI InChI=1S/C23H25N7O/c1-13-24-14(2)30(28-13)21-12-19(26-23(27-21)31-15-7-6-8-15)16-11-17(16)22-25-18-9-4-5-10-20(18)29(22)3/h4-5,9-10,12,15-17H,6-8,11H2,1-3H3/t16-,17-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...				US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3
					More data for this Ligand-Target Pair