BDBM194222 US9200001, 138

SMILES: Cc1nc(C)n(n1)-c1cc(nc(OCC2CCO2)n1)[C@@H]1C[C@H]1c1nc2ccccc2n1C

InChI Key: InChIKey=WJUZDZDISMCRCC-YJEKIOLLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM194222 (US9200001, 138) Show SMILES Cc1nc(C)n(n1)-c1cc(nc(OCC2CCO2)n1)[C@@H]1C[C@H]1c1nc2ccccc2n1C |r| Show InChI InChI=1S/C23H25N7O2/c1-13-24-14(2)30(28-13)21-11-19(26-23(27-21)32-12-15-8-9-31-15)16-10-17(16)22-25-18-6-4-5-7-20(18)29(22)3/h4-7,11,15-17H,8-10,12H2,1-3H3/t15?,16-,17-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...				US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3
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