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BDBM19426 N-(2-aminophenyl)-4-methoxybenzamide::benzamide-type inhibitor, 22

SMILES: COc1ccc(cc1)C(=O)Nc1ccccc1N

InChI Key: InChIKey=BDYVCYUXCNZYRW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19426   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 1


(Homo sapiens (human))
BDBM19426
PNG
(N-(2-aminophenyl)-4-methoxybenzamide | benzamide-t...)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C14H14N2O2/c1-18-11-8-6-10(7-9-11)14(17)16-13-5-3-2-4-12(13)15/h2-9H,15H2,1H3,(H,16,17)
PDB
MMDB

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Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



MethylGene Inc



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


J Med Chem 50: 5543-6 (2007)

More data for this
Ligand-Target Pair
Histone deacetylase 8


(Homo sapiens (human))
BDBM19426
PNG
(N-(2-aminophenyl)-4-methoxybenzamide | benzamide-t...)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C14H14N2O2/c1-18-11-8-6-10(7-9-11)14(17)16-13-5-3-2-4-12(13)15/h2-9H,15H2,1H3,(H,16,17)
PDB
MMDB

NCI pathway
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KEGG

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PC sid
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Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



MethylGene Inc



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


J Med Chem 50: 5543-6 (2007)

More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM19426
PNG
(N-(2-aminophenyl)-4-methoxybenzamide | benzamide-t...)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C14H14N2O2/c1-18-11-8-6-10(7-9-11)14(17)16-13-5-3-2-4-12(13)15/h2-9H,15H2,1H3,(H,16,17)
PDB

NCI pathway
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KEGG

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



MethylGene Inc



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


J Med Chem 50: 5543-6 (2007)

More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM19426
PNG
(N-(2-aminophenyl)-4-methoxybenzamide | benzamide-t...)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccccc1N
Show InChI InChI=1S/C14H14N2O2/c1-18-11-8-6-10(7-9-11)14(17)16-13-5-3-2-4-12(13)15/h2-9H,15H2,1H3,(H,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



MethylGene Inc



Assay Description
For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...


J Med Chem 50: 5543-6 (2007)

More data for this
Ligand-Target Pair