BDBM194504 US9200020, 2

SMILES: Nc1nc2n(CCN(CCP(O)(O)=O)CP(O)(O)=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=ZKUWINWSAOCTPV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM194504 (US9200020, 2) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H18N6O7P2/c11-10-13-8-7(9(17)14-10)12-5-16(8)2-1-15(6-25(21,22)23)3-4-24(18,19)20/h5H,1-4,6H2,(H2,18,19,20)(H2,21,22,23)(H3,11,13,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of human HGPRT by spectrophotometric assay				Bioorg Med Chem 23: 5502-10 (2015) BindingDB Entry DOI: 10.7270/Q2N58P4B
					More data for this Ligand-Target Pair
Xanthine-guanine phosphoribosyltransferase (Escherichia coli (strain K12))	BDBM194504 (US9200020, 2) Show SMILES Nc1nc2n(CCN(CCP(O)(O)=O)CP(O)(O)=O)cnc2c(=O)[nH]1 Show InChI InChI=1S/C10H18N6O7P2/c11-10-13-8-7(9(17)14-10)12-5-16(8)2-1-15(6-25(21,22)23)3-4-24(18,19)20/h5H,1-4,6H2,(H2,18,19,20)(H2,21,22,23)(H3,11,13,14,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent					Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...				US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB
					More data for this Ligand-Target Pair