null

SMILES: Oc1ccc(cc1)-c1nn2c(cc(nc2c1-c1ccc(O)cc1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=VEKHAWLAUFKERN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM19454 (4-[2-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyr...) Show SMILES Oc1ccc(cc1)-c1nn2c(cc(nc2c1-c1ccc(O)cc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11F6N3O2/c21-19(22,23)14-9-15(20(24,25)26)29-18(27-14)16(10-1-5-12(30)6-2-10)17(28-29)11-3-7-13(31)8-4-11/h1-9,30-31H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	26	-9.47	n/a	n/a	6.00E+3	n/a	n/a	7.5	0
University of Illinois at Urbana					Assay Description Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...				J Med Chem 50: 399-403 (2007) Article DOI: 10.1021/jm061035y BindingDB Entry DOI: 10.7270/Q2QZ288F
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM19454 (4-[2-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyr...) Show SMILES Oc1ccc(cc1)-c1nn2c(cc(nc2c1-c1ccc(O)cc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H11F6N3O2/c21-19(22,23)14-9-15(20(24,25)26)29-18(27-14)16(10-1-5-12(30)6-2-10)17(28-29)11-3-7-13(31)8-4-11/h1-9,30-31H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	48	-9.14	n/a	n/a	600	n/a	n/a	7.5	0
University of Illinois at Urbana					Assay Description Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...				J Med Chem 50: 399-403 (2007) Article DOI: 10.1021/jm061035y BindingDB Entry DOI: 10.7270/Q2QZ288F
					More data for this Ligand-Target Pair