null
SMILES: Oc1ccc(cc1)-c1nn2c(cc(nc2c1-c1ccc(OCCN2CCCCC2)cc1)C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=IDPLITSZGZBIIZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor (Homo sapiens (Human)) | BDBM19455 (4-(3-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7 | -10.2 | n/a | n/a | 90 | n/a | n/a | 7.5 | 0 |
University of Illinois at Urbana | Assay Description Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ... | J Med Chem 50: 399-403 (2007) Article DOI: 10.1021/jm061035y BindingDB Entry DOI: 10.7270/Q2QZ288F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM19455 (4-(3-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 71 | -8.93 | n/a | n/a | 40 | n/a | n/a | 7.5 | 0 |
University of Illinois at Urbana | Assay Description Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ... | J Med Chem 50: 399-403 (2007) Article DOI: 10.1021/jm061035y BindingDB Entry DOI: 10.7270/Q2QZ288F | |||||||||||
More data for this Ligand-Target Pair |