null
SMILES: C[C@H](Nc1nc2CCN(Cc2c(=O)n1CC#C)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=ADILCYSDZPCUMZ-INIZCTEOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolactin-releasing peptide receptor (Homo sapiens (Human)) | BDBM195613 (US9206173, 1) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5 | -11.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
OTSUKA PHARMACEUTICAL CO., LTD. US Patent | Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch... | US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolactin-releasing peptide receptor (Homo sapiens (Human)) | BDBM195613 (US9206173, 1) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | 7.4 | 25 |
OTSUKA PHARMACEUTICAL CO., LTD. US Patent | Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici... | US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS | |||||||||||
More data for this Ligand-Target Pair |