null

SMILES: COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)CSc1ccc(Cl)cc1

InChI Key: InChIKey=NRCGHCDQRHLLQE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195628 (US9206173, 2390) Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)CSc1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClF3N4O3S/c1-15(16-3-5-17(6-4-16)25(27,28)29)30-24-31-21-11-12-32(13-20(21)23(35)33(24)36-2)22(34)14-37-19-9-7-18(26)8-10-19/h3-10,15H,11-14H2,1-2H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195628 (US9206173, 2390) Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)CSc1ccc(Cl)cc1 Show InChI InChI=1S/C25H24ClF3N4O3S/c1-15(16-3-5-17(6-4-16)25(27,28)29)30-24-31-21-11-12-32(13-20(21)23(35)33(24)36-2)22(34)14-37-19-9-7-18(26)8-10-19/h3-10,15H,11-14H2,1-2H3,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair