null

SMILES: CC#CCn1c(N[C@@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc2NC(=O)CCc2c1

InChI Key: InChIKey=RJUYGBKLPBHDEW-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195650 (US9206173, 2412) Show SMILES CC#CCn1c(N[C@@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc2NC(=O)CCc2c1 |r| Show InChI InChI=1S/C30H28F3N5O3/c1-3-4-14-38-28(41)23-17-37(27(40)21-7-11-24-20(16-21)8-12-26(39)35-24)15-13-25(23)36-29(38)34-18(2)19-5-9-22(10-6-19)30(31,32)33/h5-7,9-11,16,18H,8,12-15,17H2,1-2H3,(H,34,36)(H,35,39)/t18-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195650 (US9206173, 2412) Show SMILES CC#CCn1c(N[C@@H](C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1ccc2NC(=O)CCc2c1 |r| Show InChI InChI=1S/C30H28F3N5O3/c1-3-4-14-38-28(41)23-17-37(27(40)21-7-11-24-20(16-21)8-12-26(39)35-24)15-13-25(23)36-29(38)34-18(2)19-5-9-22(10-6-19)30(31,32)33/h5-7,9-11,16,18H,8,12-15,17H2,1-2H3,(H,34,36)(H,35,39)/t18-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	259	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair