BindingDB logo
myBDB logout

null

SMILES: COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)COc1ccc(cc1)C#N

InChI Key: InChIKey=XYQWZNLPGCRSKQ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195706   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolactin-releasing peptide receptor


(Homo sapiens (Human))		BDBM195706
PNG
(US9206173, 2468)
Show SMILES COn1c(NC(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)COc1ccc(cc1)C#N
Show InChI InChI=1S/C26H24F3N5O4/c1-16(18-5-7-19(8-6-18)26(27,28)29)31-25-32-22-11-12-33(14-21(22)24(36)34(25)37-2)23(35)15-38-20-9-3-17(13-30)4-10-20/h3-10,16H,11-12,14-15H2,1-2H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6 -11.2n/an/an/an/an/a7.425



OTSUKA PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...

US Patent US9206173 (2015)


BindingDB Entry DOI: 10.7270/Q23X85FS
More data for this
Ligand-Target Pair