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BDBM195720 US9206173, 2482

SMILES: CCC(Nc1nc2CCN(Cc2c(=O)n1OC)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=IDTGMFSYCLPJPT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195720   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 10 (GPR10)


(Homo sapiens (Human))		BDBM195720
PNG
(US9206173, 2482)
Show SMILES CCC(Nc1nc2CCN(Cc2c(=O)n1OC)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C26H23F4N5O3/c1-3-21(16-5-7-17(8-6-16)26(28,29)30)32-25-33-22-10-11-34(14-19(22)24(37)35(25)38-2)23(36)18-9-4-15(13-31)12-20(18)27/h4-9,12,21H,3,10-11,14H2,1-2H3,(H,32,33)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
 8 -11.0n/an/an/an/an/a7.425



OTSUKA PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...

US Patent US9206173 (2015)


BindingDB Entry DOI: 10.7270/Q23X85FS
More data for this
Ligand-Target Pair