BDBM195722 US9206173, 2484

SMILES: CN(C)n1c(NN(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1c(F)cc(F)cc1F

InChI Key: InChIKey=YBPMETBQLYLJCH-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195722 (US9206173, 2484) Show SMILES CN(C)n1c(NN(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1c(F)cc(F)cc1F Show InChI InChI=1S/C24H22F6N6O2/c1-33(2)36-21(37)16-12-35(22(38)20-17(26)10-14(25)11-18(20)27)9-8-19(16)31-23(36)32-34(3)15-6-4-13(5-7-15)24(28,29)30/h4-7,10-11H,8-9,12H2,1-3H3,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair
Prolactin-releasing peptide receptor (Homo sapiens (Human))	BDBM195722 (US9206173, 2484) Show SMILES CN(C)n1c(NN(C)c2ccc(cc2)C(F)(F)F)nc2CCN(Cc2c1=O)C(=O)c1c(F)cc(F)cc1F Show InChI InChI=1S/C24H22F6N6O2/c1-33(2)36-21(37)16-12-35(22(38)20-17(26)10-14(25)11-18(20)27)9-8-19(16)31-23(36)32-34(3)15-6-4-13(5-7-15)24(28,29)30/h4-7,10-11H,8-9,12H2,1-3H3,(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	216	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...				US Patent US9206173 (2015) BindingDB Entry DOI: 10.7270/Q23X85FS
					More data for this Ligand-Target Pair