BDBM196131 US9211296, Table 7, Compd: 1

SMILES: CCN1CCN(CC1)c1ccc(Nc2ccnc3cc4ccccc4cc23)cc1

InChI Key: InChIKey=FGVVQTVRBTWGJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Synthesis (Vaccinia virus (strain WR))	BDBM196131 (US9211296, Table 7, Compd: 1) Show SMILES CCN1CCN(CC1)c1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 Show InChI InChI=1S/C25H26N4/c1-2-28-13-15-29(16-14-28)22-9-7-21(8-10-22)27-24-11-12-26-25-18-20-6-4-3-5-19(20)17-23(24)25/h3-12,17-18H,2,13-16H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair