BDBM196157 US9211296, Table 6, 11::US9233921, 1

SMILES: Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O

InChI Key: InChIKey=GGBJOMCSHBZQIW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM196157 (US9211296, Table 6, 11 | US9233921, 1) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-12-13(8-9)18-14(16(19)20)15(12)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196157 (US9211296, Table 6, 11 | US9233921, 1) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-12-13(8-9)18-14(16(19)20)15(12)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair