BDBM196676 US9212171, 1

SMILES: CN1C(=O)C(CC1(C)C)c1ccc(cn1)C#Cc1ccccc1

InChI Key: InChIKey=NDIYWOAWAHAYAD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5a (mGluR5) (Homo sapiens (Human))	BDBM196676 (US9212171, 1) Show SMILES CN1C(=O)C(CC1(C)C)c1ccc(cn1)C#Cc1ccccc1 Show InChI InChI=1S/C20H20N2O/c1-20(2)13-17(19(23)22(20)3)18-12-11-16(14-21-18)10-9-15-7-5-4-6-8-15/h4-8,11-12,14,17H,13H2,1-3H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...				US Patent US9212171 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TWH
					More data for this Ligand-Target Pair