BDBM196683 US9212171, 8
SMILES: CN1C(=O)C(CC1(C)C)c1ncc(cn1)C#Cc1ccc(F)cc1
InChI Key: InChIKey=UENOGSSQXGNAAF-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5a (mGluR5) (Homo sapiens (Human)) | BDBM196683 (US9212171, 8) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | 37 |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ... | US Patent US9212171 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TWH | |||||||||||
More data for this Ligand-Target Pair |