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SMILES: CN1C(=O)C(CC1(C)C)c1ccc(nn1)C#Cc1ccc(F)cc1

InChI Key: InChIKey=ABSPBXVLXKIHEO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196685   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Isoform 1 of Metabotropic glutamate receptor 5 (5a)


(Homo sapiens (Human))		BDBM196685
PNG
(US9212171, 10)
Show SMILES CN1C(=O)C(CC1(C)C)c1ccc(nn1)C#Cc1ccc(F)cc1
Show InChI InChI=1S/C19H18FN3O/c1-19(2)12-16(18(24)23(19)3)17-11-10-15(21-22-17)9-6-13-4-7-14(20)8-5-13/h4-5,7-8,10-11,16H,12H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 247n/an/an/a37



HOFFMANN-LA ROCHE INC.

US Patent


Assay Description
A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...

US Patent US9212171 (2015)


BindingDB Entry DOI: 10.7270/Q25Q4TWH
More data for this
Ligand-Target Pair