BDBM196687 US9212171, 12
SMILES: CN1C(=O)C(CCC1(C)C)c1ccc(cn1)C#Cc1ccccc1
InChI Key: InChIKey=WVSRBSUBCCOACN-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5a (mGluR5) (Homo sapiens (Human)) | BDBM196687 (US9212171, 12) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 113 | n/a | n/a | n/a | 37 |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ... | US Patent US9212171 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TWH | |||||||||||
More data for this Ligand-Target Pair |