null
SMILES: COC1(CC(C)(C)N(C)C1=O)c1ccc(cn1)C#Cc1ccccc1
InChI Key: InChIKey=ZRFISPQYTJPJAY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Homo sapiens (Human)) | BDBM196694 (US9212171, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 96 | n/a | n/a | n/a | 37 |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ... | US Patent US9212171 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TWH | |||||||||||
More data for this Ligand-Target Pair |