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SMILES: CCNc1nc(Nc2cnn(C3CCOCC3)c2Cl)ncc1C#N

InChI Key: InChIKey=ADRIKKWXVUEIOY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196729   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM196729
PNG
(US9212173, 7)
Show SMILES CCNc1nc(Nc2cnn(C3CCOCC3)c2Cl)ncc1C#N
Show InChI InChI=1S/C15H18ClN7O/c1-2-18-14-10(7-17)8-19-15(22-14)21-12-9-20-23(13(12)16)11-3-5-24-6-4-11/h8-9,11H,2-6H2,1H3,(H2,18,19,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6.20n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...

US Patent US9212173 (2015)


BindingDB Entry DOI: 10.7270/Q2222SKT
More data for this
Ligand-Target Pair