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SMILES: CNc1nc(Nc2cnn(CC3(O)CC3)c2Cl)ncc1C(F)(F)F

InChI Key: InChIKey=IJLGCNFLWATCJS-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196732   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM196732
PNG
(US9212173, 10)
Show SMILES CNc1nc(Nc2cnn(CC3(O)CC3)c2Cl)ncc1C(F)(F)F
Show InChI InChI=1S/C13H14ClF3N6O/c1-18-10-7(13(15,16)17)4-19-11(22-10)21-8-5-20-23(9(8)14)6-12(24)2-3-12/h4-5,24H,2-3,6H2,1H3,(H2,18,19,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
 5n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...

US Patent US9212173 (2015)


BindingDB Entry DOI: 10.7270/Q2222SKT
More data for this
Ligand-Target Pair