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BDBM196741 US9212173, 19

SMILES: CCNc1nc(Nc2cn(nc2C)C2(C)COC2)ncc1C(F)(F)F

InChI Key: InChIKey=KFZKLAILHANAQN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196741   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM196741
PNG
(US9212173, 19)
Show SMILES CCNc1nc(Nc2cn(nc2C)C2(C)COC2)ncc1C(F)(F)F
Show InChI InChI=1S/C15H19F3N6O/c1-4-19-12-10(15(16,17)18)5-20-13(22-12)21-11-6-24(23-9(11)2)14(3)7-25-8-14/h5-6H,4,7-8H2,1-3H3,(H2,19,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.975n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...


Citation and Details
More data for this
Ligand-Target Pair