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BDBM196827 US9212186, 24

SMILES: CNc1nc(Nc2cnn3CCCc23)ncc1C(F)(F)F

InChI Key: InChIKey=JWVVTBKLTDADEX-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196827   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM196827
PNG
(US9212186, 24)
Show SMILES CNc1nc(Nc2cnn3CCCc23)ncc1C(F)(F)F
Show InChI InChI=1S/C12H13F3N6/c1-16-10-7(12(13,14)15)5-17-11(20-10)19-8-6-18-21-4-2-3-9(8)21/h5-6H,2-4H2,1H3,(H2,16,17,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.600n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...


Citation and Details
More data for this
Ligand-Target Pair