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SMILES: Cc1nn(Cc2ccc(cc2F)-c2cc3ccc(cc3[nH]2)C(F)(F)F)c(C)c1CC(O)=O

InChI Key: InChIKey=CVEZWGPUMKBEEW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196944   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM196944
PNG
(US9206164, 5)
Show SMILES Cc1nn(Cc2ccc(cc2F)-c2cc3ccc(cc3[nH]2)C(F)(F)F)c(C)c1CC(O)=O
Show InChI InChI=1S/C23H19F4N3O2/c1-12-18(10-22(31)32)13(2)30(29-12)11-16-4-3-14(7-19(16)24)20-8-15-5-6-17(23(25,26)27)9-21(15)28-20/h3-9,28H,10-11H2,1-2H3,(H,31,32)
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US Patent
 0.5n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US9206164 (2015)


BindingDB Entry DOI: 10.7270/Q2PR7TS9
More data for this
Ligand-Target Pair