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SMILES: CCc1nn(Cc2ccc(cc2F)-c2nc3cc(F)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O

InChI Key: InChIKey=WRRWIHJVSGKXFS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM197012
PNG
(US9206164, 76)
Show SMILES CCc1nn(Cc2ccc(cc2F)-c2nc3cc(F)c(Cl)cc3[nH]2)c(CC)c1CC(O)=O
Show InChI InChI=1S/C23H21ClF2N4O2/c1-3-18-14(8-22(31)32)21(4-2)30(29-18)11-13-6-5-12(7-16(13)25)23-27-19-9-15(24)17(26)10-20(19)28-23/h5-7,9-10H,3-4,8,11H2,1-2H3,(H,27,28)(H,31,32)
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US Patent
 0.600n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US9206164 (2015)


BindingDB Entry DOI: 10.7270/Q2PR7TS9
More data for this
Ligand-Target Pair