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BDBM197028 US9206164, 92

SMILES: COc1ccc2[nH]c(nc2n1)-c1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1

InChI Key: InChIKey=KKZNFNFBZBZUIP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197028   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))
BDBM197028
PNG
(US9206164, 92)
Show SMILES COc1ccc2[nH]c(nc2n1)-c1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1
Show InChI InChI=1S/C21H20FN5O3/c1-11-15(9-19(28)29)12(2)27(26-11)10-14-5-4-13(8-16(14)22)20-23-17-6-7-18(30-3)24-21(17)25-20/h4-8H,9-10H2,1-3H3,(H,28,29)(H,23,24,25)
PDB

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PC cid
PC sid
UniChem
US Patent
0.700n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


US Patent US9206164 (2015)


BindingDB Entry DOI: 10.7270/Q2PR7TS9
More data for this
Ligand-Target Pair