BDBM197161 1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione (2)

SMILES: On1c(=O)n(CC2CC2)c2ccccc2c1=O

InChI Key: InChIKey=JAFLWTUYSKADJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (aa 1-336) (Homo sapiens (Human))	BDBM197161 (1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,...) Show SMILES On1c(=O)n(CC2CC2)c2ccccc2c1=O Show InChI InChI=1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2	PDB GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	n/a
University of Sheffield					Assay Description Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...				Nat Chem Biol 12: 815-21 (2016) Article DOI: 10.1038/nchembio.2148 BindingDB Entry DOI: 10.7270/Q2RJ4H88
					More data for this Ligand-Target Pair