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SMILES: COc1ccc(Cn2c3ccccc3c(=O)n(O)c2=O)cc1

InChI Key: InChIKey=BTUVETVDRFJMIN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197162   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Flap endonuclease 1 [1-336]


(Homo sapiens (Human))		BDBM197162
PNG
(3-hydroxy-1-(4-methoxybenzyl)quinazoline-2,4(1H,3H...)
Show SMILES COc1ccc(Cn2c3ccccc3c(=O)n(O)c2=O)cc1
Show InChI InChI=1S/C16H14N2O4/c1-22-12-8-6-11(7-9-12)10-17-14-5-3-2-4-13(14)15(19)18(21)16(17)20/h2-9,21H,10H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16.9n/an/an/an/a7.5n/a



University of Sheffield



Assay Description
Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...

Nat Chem Biol 12: 815-21 (2016)


Article DOI: 10.1038/nchembio.2148
BindingDB Entry DOI: 10.7270/Q2RJ4H88
More data for this
Ligand-Target Pair