BDBM197172 AdoHcy
SMILES: C[S+](CCC([NH3+])C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key: InChIKey=MEFKEPWMEQBLKI-YDBXVIPQSA-O
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamide N-methyltransferase (NNMT) (Homo sapiens (Human)) | BDBM197172 (AdoHcy) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.63E+4 | n/a | n/a | n/a | n/a | 8.6 | 37 |
Utrecht University | Assay Description Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ... | Biochemistry 55: 5307-15 (2016) Article DOI: 10.1021/acs.biochem.6b00733 BindingDB Entry DOI: 10.7270/Q2H130TH | |||||||||||
More data for this Ligand-Target Pair |