BDBM198751 BDBM198752::BDBM198827::US9221796, 53, P-1
SMILES: Oc1ccc(cc1)C1CCN(CC1(F)F)C1CCN(Cc2ccc(cc2)C(F)(F)F)C1=O
InChI Key: InChIKey=SVPPSJNIPGZMHE-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM198751 (BDBM198752 | BDBM198827 | US9221796, 53, P-1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.80 | -12.2 | n/a | n/a | n/a | n/a | n/a | n/a | 50 |
Bristol-Myers Squibb Company US Patent | Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo... | US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM198751 (BDBM198752 | BDBM198827 | US9221796, 53, P-1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 36 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 50 |
Bristol-Myers Squibb Company US Patent | Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo... | US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM198751 (BDBM198752 | BDBM198827 | US9221796, 53, P-1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.10E+3 | -8.80 | n/a | n/a | n/a | n/a | n/a | n/a | 50 |
Bristol-Myers Squibb Company US Patent | Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo... | US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1 | |||||||||||
More data for this Ligand-Target Pair |