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SMILES: Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1

InChI Key: InChIKey=UMACWEJWGGYMLA-UHUGOGIASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198814   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))		BDBM198814
PNG
(US9221796, 101, P-2)
Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1 |r|
Show InChI InChI=1S/C22H21ClF4N2O3/c23-17-11-14(3-6-19(17)32-21(24)25)29-10-8-18(20(29)31)28-9-7-16(22(26,27)12-28)13-1-4-15(30)5-2-13/h1-6,11,16,18,21,30H,7-10,12H2/t16?,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 11 -11.8n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...

US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair