null

SMILES: CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=PABZNWOXICIOPN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198860 (US9221797, 23) Show SMILES CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI InChI=1S/C27H36N6O/c1-26(2)10-8-19(9-11-26)22-16-20(27(3,4)33-14-12-32(5)13-15-33)6-7-23(22)31-25(34)24-29-18-21(17-28)30-24/h6-8,16,18H,9-15H2,1-5H3,(H,29,30)(H,31,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM198860 (US9221797, 23) Show SMILES CN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29| Show InChI InChI=1S/C27H36N6O/c1-26(2)10-8-19(9-11-26)22-16-20(27(3,4)33-14-12-32(5)13-15-33)6-7-23(22)31-25(34)24-29-18-21(17-28)30-24/h6-8,16,18H,9-15H2,1-5H3,(H,29,30)(H,31,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair