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SMILES: CN(C)S(=O)(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=NCNQKLBRFAJHTM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198866   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor [555-568]


(Homo sapiens (Human))		BDBM198866
PNG
(US9221797, 29)
Show SMILES CN(C)S(=O)(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:26|
Show InChI InChI=1S/C23H29N5O3S/c1-23(2)10-7-17(8-11-23)19-13-16(9-12-32(30,31)28(3)4)5-6-20(19)27-22(29)21-25-15-18(14-24)26-21/h5-7,13,15H,8-12H2,1-4H3,(H,25,26)(H,27,29)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/a7.5n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...

US Patent US9221797 (2015)


BindingDB Entry DOI: 10.7270/Q2W37V4H
More data for this
Ligand-Target Pair