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SMILES: CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C(C)(C)N1CCCCC1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198906   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor [555-568]


(Homo sapiens (Human))		BDBM198906
PNG
(US9221797, 149)
Show SMILES CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C(C)(C)N1CCCCC1 |c:5|
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/a7.5n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...

US Patent US9221797 (2015)


BindingDB Entry DOI: 10.7270/Q2W37V4H
More data for this
Ligand-Target Pair