BDBM198917 US9221802, Ex. 3
SMILES: Fc1ccc(cc1)C#Cc1ccc(nc1)N1[C@@H]2CCC[C@@H]2COC1=O
InChI Key: InChIKey=OPOPTKODSRGSJH-SJLPKXTDSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5a (mGluR5) (Homo sapiens (Human)) | BDBM198917 (US9221802, Ex. 3) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | 37 |
Hoffman-La Roche Inc. US Patent | Assay Description About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded... | US Patent US9221802 (2015) BindingDB Entry DOI: 10.7270/Q2RF5SVJ | |||||||||||
More data for this Ligand-Target Pair |