BDBM199120 N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)phenyl)-4-methylbenzenesulphonamide (8b)

SMILES: CCNc1nc(NCC)nc(n1)-n1nc(cc1-c1ccc(OC)cc1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key: InChIKey=DPGWOEYLNBRLDX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (MMP-9) (Rattus norvegicus (Rat))	BDBM199120 (N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5...) Show SMILES CCNc1nc(NCC)nc(n1)-n1nc(cc1-c1ccc(OC)cc1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C30H32N8O3S/c1-5-31-28-33-29(32-6-2)35-30(34-28)38-27(22-11-15-24(39-4)16-12-22)19-26(36-38)21-9-13-23(14-10-21)37-40-41-42-25-17-7-20(3)8-18-25/h7-19,37H,5-6H2,1-4H3,(H2,31,32,33,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair
Matrix metalloproteinase-2 (MMP-2) (Rattus norvegicus (Rat))	BDBM199120 (N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5...) Show SMILES CCNc1nc(NCC)nc(n1)-n1nc(cc1-c1ccc(OC)cc1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C30H32N8O3S/c1-5-31-28-33-29(32-6-2)35-30(34-28)38-27(22-11-15-24(39-4)16-12-22)19-26(36-38)21-9-13-23(14-10-21)37-40-41-42-25-17-7-20(3)8-18-25/h7-19,37H,5-6H2,1-4H3,(H2,31,32,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair