BDBM199178 US9217012, 6

SMILES: CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(C)=O)C(N)=O

InChI Key: InChIKey=MWNOWVUDLZPXNF-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM199178 (US9217012, 6) Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(C)=O)C(N)=O Show InChI InChI=1S/C27H35F2N4O7P/c1-3-18-7-11-20(12-8-18)25(36)31-15-5-4-6-22(24(30)35)33-26(37)23(32-17(2)34)16-19-9-13-21(14-10-19)27(28,29)41(38,39)40/h7-14,22-23H,3-6,15-16H2,1-2H3,(H2,30,35)(H,31,36)(H,32,34)(H,33,37)(H2,38,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	700	-8.39	n/a	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM199178 (US9217012, 6) Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(C)=O)C(N)=O Show InChI InChI=1S/C27H35F2N4O7P/c1-3-18-7-11-20(12-8-18)25(36)31-15-5-4-6-22(24(30)35)33-26(37)23(32-17(2)34)16-19-9-13-21(14-10-19)27(28,29)41(38,39)40/h7-14,22-23H,3-6,15-16H2,1-2H3,(H2,30,35)(H,31,36)(H,32,34)(H,33,37)(H2,38,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair