BDBM199179 US9217012, 8

SMILES: CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(C)=O)C(N)=O

InChI Key: InChIKey=VYAKAOXRMFTANB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM199179 (US9217012, 8) Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(C)=O)C(N)=O Show InChI InChI=1S/C36H44F2N5O8P/c1-3-24-12-16-27(17-13-24)33(46)40-20-8-7-11-29(32(39)45)42-35(48)31(22-26-14-18-28(19-15-26)36(37,38)52(49,50)51)43-34(47)30(41-23(2)44)21-25-9-5-4-6-10-25/h4-6,9-10,12-19,29-31H,3,7-8,11,20-22H2,1-2H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,48)(H,43,47)(H2,49,50,51)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM199179 (US9217012, 8) Show SMILES CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(C)=O)C(N)=O Show InChI InChI=1S/C36H44F2N5O8P/c1-3-24-12-16-27(17-13-24)33(46)40-20-8-7-11-29(32(39)45)42-35(48)31(22-26-14-18-28(19-15-26)36(37,38)52(49,50)51)43-34(47)30(41-23(2)44)21-25-9-5-4-6-10-25/h4-6,9-10,12-19,29-31H,3,7-8,11,20-22H2,1-2H3,(H2,39,45)(H,40,46)(H,41,44)(H,42,48)(H,43,47)(H2,49,50,51)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.0	25
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...				US Patent US9217012 (2015) BindingDB Entry DOI: 10.7270/Q2FX788H
					More data for this Ligand-Target Pair