BDBM199205 US9216998, 9

SMILES: FC(F)(F)c1c(CCc2ccccc2)n2CCCCc3cccc1c23

InChI Key: InChIKey=UCJXYPHNWBXQJX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (EL) (Mus musculus (Mouse))	BDBM199205 (US9216998, 9) Show SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCCCc3cccc1c23 Show InChI InChI=1S/C21H20F3N/c22-21(23,24)19-17-11-6-10-16-9-4-5-14-25(20(16)17)18(19)13-12-15-7-2-1-3-8-15/h1-3,6-8,10-11H,4-5,9,12-14H2	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199205 (US9216998, 9) Show SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCCCc3cccc1c23 Show InChI InChI=1S/C21H20F3N/c22-21(23,24)19-17-11-6-10-16-9-4-5-14-25(20(16)17)18(19)13-12-15-7-2-1-3-8-15/h1-3,6-8,10-11H,4-5,9,12-14H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair