BDBM199208 US9216998, 12
SMILES: CC(C)NC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F
InChI Key: InChIKey=CLSJZJZZLIGEBQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (EL) (Mus musculus (Mouse)) | BDBM199208 (US9216998, 12) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 131 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L... | US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelial lipase (Homo sapiens (Human)) | BDBM199208 (US9216998, 12) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 135 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L... | US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F | |||||||||||
More data for this Ligand-Target Pair |