BDBM199209 US9216998, 13

SMILES: CC(C)(C)OC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F

InChI Key: InChIKey=DMNPHJOBNVPTFP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (EL) (Mus musculus (Mouse))	BDBM199209 (US9216998, 13) Show SMILES CC(C)(C)OC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C25H27F3N2O2/c1-24(2,3)32-23(31)29-14-15-30-20(13-12-17-8-5-4-6-9-17)21(25(26,27)28)19-11-7-10-18(16-29)22(19)30/h4-11H,12-16H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199209 (US9216998, 13) Show SMILES CC(C)(C)OC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C25H27F3N2O2/c1-24(2,3)32-23(31)29-14-15-30-20(13-12-17-8-5-4-6-9-17)21(25(26,27)28)19-11-7-10-18(16-29)22(19)30/h4-11H,12-16H2,1-3H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair