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SMILES: FC(F)(F)CC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F

InChI Key: InChIKey=SABLNMPMLMRLTO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Mus musculus (Mouse))	BDBM199215 (US9216998, 21) Show SMILES FC(F)(F)CC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C23H20F6N2O/c24-22(25,26)13-19(32)30-11-12-31-18(10-9-15-5-2-1-3-6-15)20(23(27,28)29)17-8-4-7-16(14-30)21(17)31/h1-8H,9-14H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	237	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199215 (US9216998, 21) Show SMILES FC(F)(F)CC(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C23H20F6N2O/c24-22(25,26)13-19(32)30-11-12-31-18(10-9-15-5-2-1-3-6-15)20(23(27,28)29)17-8-4-7-16(14-30)21(17)31/h1-8H,9-14H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	255	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair