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SMILES: CS(=O)(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F

InChI Key: InChIKey=VCZPAUZUTMEULW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Mus musculus (Mouse))	BDBM199218 (US9216998, 24) Show SMILES CS(=O)(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C21H21F3N2O2S/c1-29(27,28)25-12-13-26-18(11-10-15-6-3-2-4-7-15)19(21(22,23)24)17-9-5-8-16(14-25)20(17)26/h2-9H,10-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199218 (US9216998, 24) Show SMILES CS(=O)(=O)N1CCn2c(CCc3ccccc3)c(c3cccc(C1)c23)C(F)(F)F Show InChI InChI=1S/C21H21F3N2O2S/c1-29(27,28)25-12-13-26-18(11-10-15-6-3-2-4-7-15)19(21(22,23)24)17-9-5-8-16(14-25)20(17)26/h2-9H,10-14H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	186	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair