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SMILES: FC(F)(F)c1c(CCCc2ccccc2)n2CCCCc3cccc1c23

InChI Key: InChIKey=IBLZPQQHAMGAQT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Mus musculus (Mouse))	BDBM199227 (US9216998, 11) Show SMILES FC(F)(F)c1c(CCCc2ccccc2)n2CCCCc3cccc1c23 Show InChI InChI=1S/C22H22F3N/c23-22(24,25)20-18-13-7-12-17-11-4-5-15-26(21(17)18)19(20)14-6-10-16-8-2-1-3-9-16/h1-3,7-9,12-13H,4-6,10-11,14-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM199227 (US9216998, 11) Show SMILES FC(F)(F)c1c(CCCc2ccccc2)n2CCCCc3cccc1c23 Show InChI InChI=1S/C22H22F3N/c23-22(24,25)20-18-13-7-12-17-11-4-5-15-26(21(17)18)19(20)14-6-10-16-8-2-1-3-9-16/h1-3,7-9,12-13H,4-6,10-11,14-15H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	7.2	n/a
Janssen Pharmaceutica NV US Patent					Assay Description To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND® 384-well plates (Corning, L...				US Patent US9216998 (2015) BindingDB Entry DOI: 10.7270/Q22N513F
					More data for this Ligand-Target Pair