null
SMILES: CC1(C)COCCN1C(=O)c1ccc(cn1)C#Cc1cccc(F)c1
InChI Key: InChIKey=ZFKBTPPHOPDBMS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 1 of Metabotropic glutamate receptor 5 (5a) (Homo sapiens (Human)) | BDBM199987 (US9227959, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 72 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Hoffman-La Roche Inc. US Patent | Assay Description For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ... | US Patent US9227959 (2016) BindingDB Entry DOI: 10.7270/Q25D8QNJ | |||||||||||
More data for this Ligand-Target Pair |