BDBM200320 US9227956, 5

SMILES: Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cn1)-n1nnc2cccnc12

InChI Key: InChIKey=OZBMIGDQBBMIRA-CQSZACIVSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 200320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM200320 (US9227956, 5) Show SMILES Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cn1)-n1nnc2cccnc12 |r| Show InChI InChI=1S/C21H19ClN8O/c22-16-5-2-10-24-19(16)29(14-4-1-9-23-12-14)21(31)18-8-7-15(13-26-18)30-20-17(27-28-30)6-3-11-25-20/h2-3,5-8,10-11,13-14,23H,1,4,9,12H2/t14-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of dofetilide binding to human ERG by fluorescence polarization assay				J Med Chem 61: 5704-5718 (2018) Article DOI: 10.1021/acs.jmedchem.8b00650 BindingDB Entry DOI: 10.7270/Q28C9ZRR
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 9 (PCSK9) (Homo sapiens (Human))	BDBM200320 (US9227956, 5) Show SMILES Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cn1)-n1nnc2cccnc12 |r| Show InChI InChI=1S/C21H19ClN8O/c22-16-5-2-10-24-19(16)29(14-4-1-9-23-12-14)21(31)18-8-7-15(13-26-18)30-20-17(27-28-30)6-3-11-25-20/h2-3,5-8,10-11,13-14,23H,1,4,9,12H2/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...				US Patent US9227956 (2016) BindingDB Entry DOI: 10.7270/Q20R9N7M
					More data for this Ligand-Target Pair