BDBM200334 US9227956, 18
SMILES: Cc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-c1cnn(C)c1-c1noc(=O)[nH]1
InChI Key:
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proprotein convertase subtilisin/kexin type 9 (PCSK9) (Homo sapiens (Human)) | BDBM200334 (US9227956, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo... | US Patent US9227956 (2016) BindingDB Entry DOI: 10.7270/Q20R9N7M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proprotein convertase subtilisin/kexin type 9 (PCSK9) (Homo sapiens (Human)) | BDBM200334 (US9227956, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com... | US Patent US9227956 (2016) BindingDB Entry DOI: 10.7270/Q20R9N7M | |||||||||||
More data for this Ligand-Target Pair |