Found 5 hits for monomerid = 200513 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
B-RAF V600E
(Homo sapiens (Human)) | BDBM200513
(US9670231, 1.35)Show SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1 | PDB
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
BeiGene, Ltd.
US Patent
| Assay Description
TBD |
US Patent US9670231 (2017)
BindingDB Entry DOI: 10.7270/Q2F18WWF |
More data for this
Ligand-Target Pair | |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM200513
(US9670231, 1.35)Show SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a |
BeiGene, Ltd.
US Patent
| Assay Description
TBD |
US Patent US9670231 (2017)
BindingDB Entry DOI: 10.7270/Q2F18WWF |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor(L858R, T790M)
(Homo sapiens (Human)) | BDBM200513
(US9670231, 1.35)Show SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1 | PDB
MMDB
KEGG
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
BeiGene, Ltd.
US Patent
| Assay Description
TBD |
US Patent US9670231 (2017)
BindingDB Entry DOI: 10.7270/Q2F18WWF |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor(L858R)
(Homo sapiens (Human)) | BDBM200513
(US9670231, 1.35)Show SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1 | PDB
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
BeiGene, Ltd.
US Patent
| Assay Description
TBD |
US Patent US9670231 (2017)
BindingDB Entry DOI: 10.7270/Q2F18WWF |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM200513
(US9670231, 1.35)Show SMILES FC(F)(F)c1cccc(c1)C(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI InChI=1S/C25H18F3N3O4/c26-25(27,28)13-3-1-2-12(10-13)24(33)31-21-20-16-11-14(4-6-17(16)35-22(20)21)34-18-8-9-29-23-15(18)5-7-19(32)30-23/h1-4,6,8-11,20-22H,5,7H2,(H,31,33)(H,29,30,32)/t20-,21-,22-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
BeiGene, Ltd.
US Patent
| Assay Description
TBD |
US Patent US9670231 (2017)
BindingDB Entry DOI: 10.7270/Q2F18WWF |
More data for this
Ligand-Target Pair | |
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