BDBM20064 5-Substituted-6-chlorouracil, 7d::6-chloro-5-[(2E)-pent-2-en-3-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

SMILES: CCC(=CC)c1c(Cl)[nH]c(=O)[nH]c1=O

InChI Key: InChIKey=NNGFJMXOLQUROP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine Phosphorylase (TP) (Homo sapiens (Human))	BDBM20064 (5-Substituted-6-chlorouracil, 7d | 6-chloro-5-[(2E...) Show SMILES CCC(=CC)c1c(Cl)[nH]c(=O)[nH]c1=O |w:3.3| Show InChI InChI=1S/C9H11ClN2O2/c1-3-5(4-2)6-7(10)11-9(14)12-8(6)13/h3H,4H2,1-2H3,(H2,11,12,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	490	-8.95	n/a	n/a	n/a	n/a	n/a	6.4	37
Gilead Sciences Inc.					Assay Description The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...				J Med Chem 50: 6016-23 (2007) Article DOI: 10.1021/jm070644i BindingDB Entry DOI: 10.7270/Q2M043PX
					More data for this Ligand-Target Pair