BDBM20074 6-Methyl-5-phenylpyrimidine-2,4(1H,3H)-dione, 16::6-methyl-5-phenyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

SMILES: Cc1[nH]c(=O)[nH]c(=O)c1-c1ccccc1

InChI Key: InChIKey=ZJXKXMDSYRKTNA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine Phosphorylase (TP) (Homo sapiens (Human))	BDBM20074 (6-Methyl-5-phenylpyrimidine-2,4(1H,3H)-dione, 16 |...) Show SMILES Cc1[nH]c(=O)[nH]c(=O)c1-c1ccccc1 Show InChI InChI=1S/C11H10N2O2/c1-7-9(8-5-3-2-4-6-8)10(14)13-11(15)12-7/h2-6H,1H3,(H2,12,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>2.00E+4	>-6.66	n/a	n/a	n/a	n/a	n/a	6.4	37
Gilead Sciences Inc.					Assay Description The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...				J Med Chem 50: 6016-23 (2007) Article DOI: 10.1021/jm070644i BindingDB Entry DOI: 10.7270/Q2M043PX
					More data for this Ligand-Target Pair